Research Article Synergistic drug combinations designed to fully suppress SARS-CoV-2 in the lung of COVID-19 patients, published in PLoS ONE, November 2022.
In this study the impact of drug combinations on severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) suppression has been assessed. While as monotherapy they were not potent, the combination of the same drugs effectively suppressed SARS-CoV-2.
Media Coverage
Exploring antiviral drug combinations for SARS-CoV-2 suppression
The Medical News, 14 Nov 2022
Erforschung antiviraler Wirkstoffkombinationen zur Unterdrückung von SARS-CoV-2 ~ Nach Welt
Nachrichten Welt, 15 Nov 2022
Lendlease and Elettronica Spa announce the event “Towards a new normal, solutions for life after the pandemic”. The event will take place in Milan at MINDMilano Innovation District, on 20 June 2022.
It’s the presentation of a revolutionary system of Biodefense for the inactivation of viruses, even in their possible variants, and of a wider project for environmental safety.
The technology has been conceived by Elettronica, a company operating in the electronic defense sector, and implemented in MIND through the collaboration with Lendlease, leading international property and investments group in order to create a new post-pandemic ecosystem that can be achieved only by ensuring safety in all environments.
Dr. Lori will be a Speaker at this important initiative. To view the registration of the event, please click here.
More information about the technology: E4SHIELD, the innovative hi-tech air protection system that disable the virus around you. Available in wearable and wall fixed version.
ViroStatics and biotx.ai to partner in developing CDK6 inhibitors for the treatment of acute respiratory distress syndrome (ARDS) and COVID-19
ViroStatics and biotx.ai have signed a memorandum of understanding as the basis to jointly develop CDK6 inhibitors for ARDS. This will close major therapeutic gaps in the treatment of COVID-19 and better prepare the world for future SARS pandemics.
In detail, in order to develop more specialized CDK6 treatments, the two Companies will develop and investigate ViroStatics’ CDK6 inhibitor VS2-370.
Early results are promising and we are optimistic that we will make major contributions to the development of drugs against all COVID-19 variants, future SARS pandemics, and ARDS.
From the journal: Biomaterials Science
Blocking viral infections with lysine-based polymeric nanostructures: a critical review – published in Biomaterials Science.
The outbreak of the Covid-19 pandemic due to the SARS-CoV-2 coronavirus has accelerated the search for innovative antivirals with possibly broad-spectrum efficacy. One of the possible strategies is to inhibit the replication of the virus by preventing or limiting its entry into the cells. Nanomaterials derived from lysine, an essential amino acid capable of forming homopeptides of different shapes and sizes through thermal polymerization, are an exciting antiviral option.
The Report relates to the Global Cyclin Dependent Kinase 6 Market Size, Trends, Growth, Competitive Landscape and Key Regional Analysis to 2027” offering a broad information and understanding of the Cyclin Dependent Kinase 6 markets. The report analyses the Cyclin Dependent Kinase 6 market for the historical (2016–2020) and forecast (2021–2027) periods. The report includes drivers, restraints and opportunities influencing the market, market size analysis with respect to revenue. The report also provides a snapshot of the competitive landscape of the key players operating in the market along with the percentage market share of the top players. The report has a section on the impact of COVID-19 on the Cyclin Dependent Kinase 6 market at the global and country levels.. It is a detailed Report of insights from leading-executive voices across the value chain, from the country’s foundational APIs and CDMO industry, to cutting-edge innovators in oncology, rare diseases, ophthalmology, and many others.
About Reports Globe
RG offers comprehensive data analysis and business research services designed to provide with in-depth knowledge needed to make complex decisions in the business area.
Global Business Reports (GBR) published the first Digital Version of Italy Life Sciences Report – 2021. It is a detailed Report of insights from leading-executive voices across the value chain, from the country’s foundational APIs and CDMO industry, to cutting-edge innovators in oncology, rare diseases, ophthalmology, and many others.
You can find, within the Digital Italy Life Sciences 2021 Publication, mentions of ViroStatics and quotations within the editorial at Page 36, 43 and 47.
About GBR
Headquartered in Singapore and with offices in Istanbul, Global Business Reports (GBR) was established in 2001 in order to provide up to date and first hand information for global business decision makers.In an age where cross boundary trade and investment and the globalization process are the driving factors for latest businesses, information is crucial. Precise sectorial reports help companies understand and expand their markets, improve their sourcing chain, target their investments and discover the trends affecting their industry around the world.
Our CEO, Franco Lori, has been recently interviewed by Global Business Reports (GBR)
Our CEO, Franco Lori, has been recently interviewed by Global Business Reports (GBR), presenting ViroStatics’ programs on antiviral and anticancer compounds as well as our tailored services to test drugs, disinfectants and devices against SARS-CoV-2.
About GBR
Headquartered in Singapore and with offices in Istanbul, Global Business Reports (GBR) was established in 2001 in order to provide up to date and first hand information for global business decision makers.In an age where cross boundary trade and investment and the globalization process are the driving factors for latest businesses, information is crucial. Precise sectorial reports help companies understand and expand their markets, improve their sourcing chain, target their investments and discover the trends affecting their industry around the world.
ViroStatics’ Services have been peer-reviewed. Article published in Precision Nanomedicine
This Technical Note describes the background, instrumentation, and expertise of ViroStatics to test drugs, materials, or devices against various strains of SARS-CoV-2.
Precision Nanomedicine (PRNANO) is a platinum open access, peer-reviewed international journal (E-ISSN:2639-9431), the official journal of the European Foundation for Clinical Nanomedicine (CLINAM).
The journal is endorsed by the European Society for Nanomedicine (ESNAM), by the International Society for Nanomedicine (ISNM, Basel), and supported by the British Society for Nanomedicine.
ViroStatics and biotx.ai to partner in developing CDK6 inhibitors for the treatment of acute respiratory distress syndrome (ARDS) and COVID-19
ViroStatics and biotx.ai have signed a memorandum of understanding as the basis to jointly develop CDK6 inhibitors for ARDS. This will close major therapeutic gaps in the treatment of COVID-19 and better prepare the world for future SARS pandemics.
In detail, in order to develop more specialized CDK6 treatments, the two Companies will develop and investigate ViroStatics’ CDK6 inhibitor VS2-370.
Early results are promising and we are optimistic that we will make major contributions to the development of drugs against all COVID-19 variants, future SARS pandemics, and ARDS.
From the journal: Biomaterials Science
Blocking viral infections with lysine-based polymeric nanostructures: a critical review – published in Biomaterials Science.
The outbreak of the Covid-19 pandemic due to the SARS-CoV-2 coronavirus has accelerated the search for innovative antivirals with possibly broad-spectrum efficacy. One of the possible strategies is to inhibit the replication of the virus by preventing or limiting its entry into the cells. Nanomaterials derived from lysine, an essential amino acid capable of forming homopeptides of different shapes and sizes through thermal polymerization, are an exciting antiviral option.
The Report relates to the Global Cyclin Dependent Kinase 6 Market Size, Trends, Growth, Competitive Landscape and Key Regional Analysis to 2027” offering a broad information and understanding of the Cyclin Dependent Kinase 6 markets. The report analyses the Cyclin Dependent Kinase 6 market for the historical (2016–2020) and forecast (2021–2027) periods. The report includes drivers, restraints and opportunities influencing the market, market size analysis with respect to revenue. The report also provides a snapshot of the competitive landscape of the key players operating in the market along with the percentage market share of the top players. The report has a section on the impact of COVID-19 on the Cyclin Dependent Kinase 6 market at the global and country levels.. It is a detailed Report of insights from leading-executive voices across the value chain, from the country’s foundational APIs and CDMO industry, to cutting-edge innovators in oncology, rare diseases, ophthalmology, and many others.
About Reports Globe
RG offers comprehensive data analysis and business research services designed to provide with in-depth knowledge needed to make complex decisions in the business area.
Global Business Reports (GBR) published the first Digital Version of Italy Life Sciences Report – 2021. It is a detailed Report of insights from leading-executive voices across the value chain, from the country’s foundational APIs and CDMO industry, to cutting-edge innovators in oncology, rare diseases, ophthalmology, and many others.
You can find, within the Digital Italy Life Sciences 2021 Publication, mentions of ViroStatics and quotations within the editorial at Page 36, 43 and 47.
About GBR
Headquartered in Singapore and with offices in Istanbul, Global Business Reports (GBR) was established in 2001 in order to provide up to date and first hand information for global business decision makers.In an age where cross boundary trade and investment and the globalization process are the driving factors for latest businesses, information is crucial. Precise sectorial reports help companies understand and expand their markets, improve their sourcing chain, target their investments and discover the trends affecting their industry around the world.
Our CEO, Franco Lori, has been recently interviewed by Global Business Reports (GBR)
Our CEO, Franco Lori, has been recently interviewed by Global Business Reports (GBR), presenting ViroStatics’ programs on antiviral and anticancer compounds as well as our tailored services to test drugs, disinfectants and devices against SARS-CoV-2.
About GBR
Headquartered in Singapore and with offices in Istanbul, Global Business Reports (GBR) was established in 2001 in order to provide up to date and first hand information for global business decision makers.In an age where cross boundary trade and investment and the globalization process are the driving factors for latest businesses, information is crucial. Precise sectorial reports help companies understand and expand their markets, improve their sourcing chain, target their investments and discover the trends affecting their industry around the world.
ViroStatics’ Services have been peer-reviewed. Article published in Precision Nanomedicine
This Technical Note describes the background, instrumentation, and expertise of ViroStatics to test drugs, materials, or devices against various strains of SARS-CoV-2.
Precision Nanomedicine (PRNANO) is a platinum open access, peer-reviewed international journal (E-ISSN:2639-9431), the official journal of the European Foundation for Clinical Nanomedicine (CLINAM).
The journal is endorsed by the European Society for Nanomedicine (ESNAM), by the International Society for Nanomedicine (ISNM, Basel), and supported by the British Society for Nanomedicine.
ViroStatics and biotx.ai to partner in developing CDK6 inhibitors for the treatment of acute respiratory distress syndrome (ARDS) and COVID-19
ViroStatics and biotx.ai have signed a memorandum of understanding as the basis to jointly develop CDK6 inhibitors for ARDS. This will close major therapeutic gaps in the treatment of COVID-19 and better prepare the world for future SARS pandemics.
In detail, in order to develop more specialized CDK6 treatments, the two Companies will develop and investigate ViroStatics’ CDK6 inhibitor VS2-370.
Early results are promising and we are optimistic that we will make major contributions to the development of drugs against all COVID-19 variants, future SARS pandemics, and ARDS.
From the journal: Biomaterials Science
Blocking viral infections with lysine-based polymeric nanostructures: a critical review – published in Biomaterials Science.
The outbreak of the Covid-19 pandemic due to the SARS-CoV-2 coronavirus has accelerated the search for innovative antivirals with possibly broad-spectrum efficacy. One of the possible strategies is to inhibit the replication of the virus by preventing or limiting its entry into the cells. Nanomaterials derived from lysine, an essential amino acid capable of forming homopeptides of different shapes and sizes through thermal polymerization, are an exciting antiviral option.
The Report relates to the Global Cyclin Dependent Kinase 6 Market Size, Trends, Growth, Competitive Landscape and Key Regional Analysis to 2027” offering a broad information and understanding of the Cyclin Dependent Kinase 6 markets. The report analyses the Cyclin Dependent Kinase 6 market for the historical (2016–2020) and forecast (2021–2027) periods. The report includes drivers, restraints and opportunities influencing the market, market size analysis with respect to revenue. The report also provides a snapshot of the competitive landscape of the key players operating in the market along with the percentage market share of the top players. The report has a section on the impact of COVID-19 on the Cyclin Dependent Kinase 6 market at the global and country levels.. It is a detailed Report of insights from leading-executive voices across the value chain, from the country’s foundational APIs and CDMO industry, to cutting-edge innovators in oncology, rare diseases, ophthalmology, and many others.
About Reports Globe
RG offers comprehensive data analysis and business research services designed to provide with in-depth knowledge needed to make complex decisions in the business area.
Global Business Reports (GBR) published the first Digital Version of Italy Life Sciences Report – 2021. It is a detailed Report of insights from leading-executive voices across the value chain, from the country’s foundational APIs and CDMO industry, to cutting-edge innovators in oncology, rare diseases, ophthalmology, and many others.
You can find, within the Digital Italy Life Sciences 2021 Publication, mentions of ViroStatics and quotations within the editorial at Page 36, 43 and 47.
About GBR
Headquartered in Singapore and with offices in Istanbul, Global Business Reports (GBR) was established in 2001 in order to provide up to date and first hand information for global business decision makers.In an age where cross boundary trade and investment and the globalization process are the driving factors for latest businesses, information is crucial. Precise sectorial reports help companies understand and expand their markets, improve their sourcing chain, target their investments and discover the trends affecting their industry around the world.
Our CEO, Franco Lori, has been recently interviewed by Global Business Reports (GBR)
Our CEO, Franco Lori, has been recently interviewed by Global Business Reports (GBR), presenting ViroStatics’ programs on antiviral and anticancer compounds as well as our tailored services to test drugs, disinfectants and devices against SARS-CoV-2.
About GBR
Headquartered in Singapore and with offices in Istanbul, Global Business Reports (GBR) was established in 2001 in order to provide up to date and first hand information for global business decision makers.In an age where cross boundary trade and investment and the globalization process are the driving factors for latest businesses, information is crucial. Precise sectorial reports help companies understand and expand their markets, improve their sourcing chain, target their investments and discover the trends affecting their industry around the world.
ViroStatics’ Services have been peer-reviewed. Article published in Precision Nanomedicine
This Technical Note describes the background, instrumentation, and expertise of ViroStatics to test drugs, materials, or devices against various strains of SARS-CoV-2.
Precision Nanomedicine (PRNANO) is a platinum open access, peer-reviewed international journal (E-ISSN:2639-9431), the official journal of the European Foundation for Clinical Nanomedicine (CLINAM).
The journal is endorsed by the European Society for Nanomedicine (ESNAM), by the International Society for Nanomedicine (ISNM, Basel), and supported by the British Society for Nanomedicine.
ViroStatics among the best Italy-based Pharmaceutical companies Best Startup.eu
Companies were selected across the size spectrum from cutting edge startups to established brands.
Startups and companies listed were chosen for exceptional performance in one of these categories:
ViroStatics has received the label InvestHorizon – Accelerated
The InvestHorizon Accelerated label is for selected deep tech companies from the accelerator programme to facilitate series A funding.
This quality label is a guarantee for investors to find high standard project proposals from European SMEs with growth potential.
InvestHorizon is a programme financed by the European Commission in association with Eureka to foster investment readiness.
ViroStatics awarded with H2020 Seal of Excellence (to view the document please click here Seal of Excellence 2020)
Project proposal 970239 TOSCA “A Novel CDK4/6/9 Inhibitor for the Treatment of Aggressive Cancers”
Horizon 2020’s SME Instrument (grant only and blended finance) call H2020-EIC-SMEInst-2018-2020 (H2020-EIC-SMEInst-2018-2020-3) of 7 October 2020 in the area of EIC-SMEInst-2018-2020 SME instrument
ViroStatics selected by Meet in Italy for Life Sciences
ViroStatics is among the finalists to pitch its presentation in virtual mode.
Meet in Italy for Life Sciences is the leading national matchmaking and update event on Life Sciences.
Health-related innovations are among the key elements that influence the progress of mankind, the environment in which we live, and our wellbeing. Speaking about health, therefore, does not mean simply speaking about investments and costs, but rather about an absolute value that sees in technological innovation and scientific research the fundamental elements of growth.
ViroStatics has been selected to present its business proposal refined through tailored sessions with life sciences expert, coaches, investors, that allowed unleashing its full potential and improved its business approach and the communication of its innovation value.
ViroStatics is now fully equipped to test any compound (small molecule and/or biologic) against SARS-CoV-2
ViroStatics scientists have >30 years experience testing antivirals, including double and triple drug combinations, both in the laboratory and in the clinics, leading to the description of the first functional cure of an HIV infected patient (the Berlin Patient, New England Journal of Medicine, 1999).
If you are interested to have any compound tested by us, please contact ViroStatics CSO, Davide De Forni, at d.deforni@virostatics.com
ViroStatics is engaged to fight against COVID-19
The Coronavirus pandemic (COVID-19) is in everyone’s mind and heart. We assure you that we are putting all our forces into action to fight it. Help us identifying with our research as many drugs as possible to be made immediately available to our doctors. Help our search.
Interview (in Italian): TV Parma https://www.gazzettadiparma.it/mediagallery/tv-parma/2020/03/18/news/il_ricercatore_franco_lori_puntare_subito_su_un_cocktail_dei_farmaci_esistenti_poi_il_vaccino_-_video-2956153/
Article (in Italian): Panorama https://www.panorama.it/news/salute/novita-nella-ricerca-alla-cura-per-il-covid-19
ViroStatics awarded with H2020 Seal of Excellence (to view the document please click here Seal of Excellence 2019)
“TOSCA” project proposal, aiming at reaching clinical readiness for VS2-370, a novel oral CDK4/6/9 inhibitor developed for the treatment of aggressive tumors (breast, lung, pancreas, haemato-oncology), for out-licensing or M&A with a Pharmaceutical Company, has been judged as a high quality proposal following highly competitive evaluation process by an international panel of independent experts and has been therefore awarded with the SEAL OF EXCELLENCE within the Horizon 2020’s SME instrument Phase 2 call H2020-EIC-SMEInst-2018-2020. Horizon 2020 is the biggest EU Research and Innovation programme ever for breakthroughs, discoveries and world-firsts by taking great ideas from the lab to the market.
BioTrinity, London, UK
BIO-EUROPE 2018, Copenhagen, Denmark
ViroStatics has been certified by AIFA as Phase I Clinical Trial Laboratory
In 2015, the Italian Medicines Agency (Agenzia Italiana del Farmaco; AIFA) issued the Determination 809/2015 with new requirements for phase I clinical trials. The new AIFA Determination imposes a certified organizational model on units and laboratories involved in phase I trials.
ViroStatics is now inserted in the list of certified Phase I Clinical Trials sites available on AIFA website at this link http://www.aifa.gov.it/sites/default/files/2018_07_24_Elenco_Strutture_Fase_I.pdf.
Meet In Italy for Life Sciences and Italian Healthcare Venture Forum 2017, Turin, Italy
ViroStatics has been selected to present at the Italian Healthcare Venture Forum 2017, taking place on October, 11-12th 2017 at the Torino Incontra Congress Centre in Turin, Italy. Our company is among the top 20 companies selected by the Selection Committee out of more than 70 innovative companies that have applied for the event.
ViroStatics will be also attending the partnering event Meet in Italy for Life Sciences.
The event stretches over three intensive (net)working days, during which business meetings, networking activities, pitching sessions, thematic workshops and, at the end, a convention on the life sciences key trends and innovation strategies will take place.
The event offers high visibility and opportunities for businesses and networking, creating dedicated dialogues between national and international, public and private stakeholders, by networking research-driven innovation.
ViroStatics has successfully concluded the Project “Thunder” under Horizon 2020 dedicated SME Instrument
“Thunder” project represents a feasibility study about the development of the innovative CDK inhibitor VS2-370 with a dual pronged applicability: treats certain HIV-associated cancers while simultaneously purging the HIV reservoirs which continue to threaten individuals suffering from AIDS. This dual pronged approach provides a clear pathway for regulatory approval which is not available to those drugs under development which are HIV specific. We achieved proof of concept demonstrating activity of the drug in vitro and in vivo in a relevant model of HIV-associated tumors (i.e Non-Hodgkin Primary Effusion Lymphoma, PEL).
During the project we have completed the documentation on VS2-370 intended for Pharmas and reached out to 34 likely potential future oncology-oriented partners with the primary goal to educate them ahead of a formal process after further pre-clinical studies. We have received positive feedbacks and agreed to proceed with the development of the product by completing the studies necessary for the Investigational Medicinal Product Dossier to allow the Pharma partner to run the first-in-man clinical trial.
Startup Olé 2017, Salamanca, Spain
Being a Seal of Excellence holder, ViroStatics has been selected to attend the event Startup Olé in Salamanca.
Startup Olé includes a Startup Fair, a Pitching Competition and Curated Matchmaking with relevant corporates and investors and private networking. SMEs will have the opportunity to present their business, pitch to investors, attend workshops, network and much more.
BIO-EUROPE SPRING, Barcelona
Thunder Project selected for Phase I SME instrument by the European Community
Jadranka Rogan, MD, PhD joined the Team as Head of Clinical Development
She brings expertise in clinical oncology. In her 25 years service to Pharma Industry she covered positions of Medical director for Farmitalia Carlo Erba office for Eastern Europe, CSC Pharmaceuticals and Cyathus Exquirere, Vienna. Also she ran the Regulatory affairs office and Pharmacovigilance for CSC Pharmaceuticals and was Qualified person for Pharmacovigilance (EUQPPV) for Cyathus Exquirere. Currently, she is CEO of Inphares GmbH, a network of professionals with expertise in diverse fields of pharmaceutical research and development.
ViroStatics awarded with H2020 Seal of Excellence (to view the document please click here Seal of Excellence 2016)
The project proposal THAMAR related to the development of our CDK inhibitor to target HIV-associated malignancies and to purge viral reservoir submitted under the Horizon 2020’s SME instrument phase 1 call H2020-SME Inst-2016-2017 in the area of Dedicated support to biotechnology SMEs closing the gap from lab to market by ViroStatics following evaluation by an international panel of independent experts was successful in a highly competitive evaluation process as an innovative project proposal.